Core Biotechnology Services Electron Microscopy Facility

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The EMF offers preparation, imaging and analysis of biological samples for EM including CLEM, volume EM and elemental analysis. The facility houses a TEM, FEGSEM, ultramicrotomes, coating unit, critical point dryer and wetlab. Staff are experienced in techniques including negative staining, ultramicrotomy, immunogold labelling and SEM sample preparation and offer sample prep and advice for Correlative Light and Electron Microscopy (CLEM) and 3D-EM. Samples include viruses, proteins, nanoparticles, bacteria, cell cultures, tissues and model organisms and staff have experience with clinical biopsies, forensic material and CII & CIII hazardous organisms. EMF staff are happy to discuss either a brief service or longer collaborative arrangements. Regular users are offered training. Key Equipment: JEOL JEM-1400 120KV TEM; Zeiss Gemini 360 FEGSEM; Oxford Instruments Ultim Extreme EDS Detector

Key contact name:

Natalie Allcock

Key contact email address:

nsa2@leicester.ac.uk

Website link:

www.le.ac.uk/cbs-em

Telephone number:

+44 (0)116 252 3370

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